Total synthesis of steroid hormones

Camphor was a scarce and expensive natural product with a worldwide demand. [ when? ] [ according to whom? ] Haller and Blanc synthesized camphor from camphor acid; [ when? ] [2] however, the precursor, camphoric acid, was of unknown structure. When Finnish chemist Gustav Komppa synthesized camphoric acid from diethyl oxalate and 3,3-dimethylpentanoic acid in 1904, the structure of these precursors allowed chemists at the time to infer the complicated ring structure of camphor. Shortly thereafter, [ when? ] William Perkin published another synthesis of camphor. [ relevant? – discuss ] The work on the total chemical synthesis of camphor allowed Komppa to begin industrial production of this compound, in Tainionkoski, Finland , in 1907.

Total synthesis of steroid hormones

total synthesis of steroid hormones

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