It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
For the athlete looking for an edge a dosing of 20mg per day will generally prove to be the minimal with 40mg per day being far more optimal. While 40mg per day will provide a nice boost in-terms of overall athletic performance if you’re really looking to transform your physique you will probably need a far greater dose. As this steroid will not provide massive amounts of lean tissue most bodybuilders will not mess with it and if they do they will necessarily take massive amounts making it a poor choice for off-season periods of growth. The dieting bodybuilder however might find a more suitable use for the steroid but again there are more efficient choices for this individual. In either case, as it is an anabolic steroid that is hepatic total use should not extend past the 8 week mark but many will find 6 weeks to be just about perfect.
For the female Turinabol user 5mg per day would be the starting point with 10mg per day being the absolute max . Most females will need to start at 5mg per day to see how they react but understand if you approach the 10mg mark you will increase the probability of virilization. While 5mg per day may not sound like much it is important to remember on a per milligram basis Turinabol appears to be much stronger in women than it is in men meaning lower doses will have a far reaching and pronounced affect.