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Such molecular profiling is not new to the field of oncology. For decades, the use of the hormone receptor modulator tamoxifen (Nolvadex, brand no longer available in the United States) has been limited to the two thirds of patients with breast cancer whose tumors express estrogen or progesterone receptors. 26 However, treatment effectiveness does not always correlate with molecular biology. The effect of cetuximab (Erbitux), an anti-EGFR monoclonal antibody used in the treatment of colorectal cancer, is independent of the degree of EGFR expression in the tumor. 27

For further information: For further information: Novartis Media Relations: Julie Masow, Novartis Consumer Health, Inc., Communications, (973) 503-7663 (direct), (862) 579-8456 (mobile), @; Silvie Letendre, Novartis Pharmaceuticals Canada Communications, (514) 633-7872 (direct), (514) 449 7872 (mobile), @, e-mail: @; Cohn & Wolfe: Lorena Cordoba, Cohn & Wolfe, (416) 924-5700 ext. 4089, @; Alexis Beamer, Cohn & Wolfe, (416) 924-5700 ext. 4031, @; Mélissa Maloul-Cohen, Cohn & Wolfe, (514) 845-2257, @

New generation topical steroid

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