Steroids can also increase the process of male baldness specifically in predisposed users. Because the natural testosterone of human body is not required when anabolic steroids are used, the body halts generating its own testosterone supply which results in testicles shrinking. Abuse of steroids can result in the significant rise of blood pressure due to their overall ability to increase red blood cell count. The steroids users are more exposed to ‘Roid Rage’ or increased aggression. Evidence suggests that abuse of anabolic steroids significantly increase aggressive and violent behavior among some users.
A decrease in the effectiveness of OCPs is a concern with coadministration of oral antibiotics. Although this concern has not been supported by research, some package inserts contain a warning about decreased OCP efficacy with concomitant ampicillin or tetracycline therapy. A review of pharmokinetic data showed a reduction of contraceptive steroid hormones only with concomitant use of rifampin (Rifadin). 24 [Evidence level B, nonquantitative systematic review] Nonetheless, it may be wise to inform patients receiving oral antibiotic therapy about the possibility of OCP failure, and to recommend the use of a second method of contraception.